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Publication details

Document type
Journal articles

Document subtype
Full paper

Title
Undaria pinnatifida (U. pinnatifida) bioactivity: antioxidant, gastro-intestinal motility, cholesterol biosynthesis and liver cell lines proteome

Participants in the publication
Pedro B. (Author)
Guedes L. (Author)
André R (Author)
Gaspar M.H. (Author)
Dep. Química e Bioquímica
 BioISI
 Vaz P. (Author)
Ascensão L. (Author)
Dep. Biologia Vegetal
 CESAM
 Melo R. (Author)
Dep. Biologia Vegetal
 MARE
 Serralheiro M.L. (Author)
Dep. Química e Bioquímica
 BioISI
Summary
Undaria pinnatifida is a brown alga, largely used as food in oriental countries. The purpose of this work was to analyze several bioactivities that might be present in different food preparations, relating them with the compounds present in the extracts. Aqueous extracts cooked, like a soup, as well as used in a salad, by simulating U. pinnatifida digestion with pancreatin were prepared. The soup preparation had anti-acetylcholinesterase activity as well as 3-hydroxy3-methyl-glutaryl coenzyme A reductase inhibition capacity, the use of 1 mg/mL, for both enzymes, caused 50% enzyme activity inhibition. The extracts produced changes in HepG2 cell proteome, mainly in the 148 kDa proteins. U. pinnatifida in salads hardly released phlorotannins to the digestive tract. The in vitro studies suggested that a soup prepared from this seaweed could deliver bioactive compounds, phlorotannins and small peptides that may facilitate the gastro-intestinal motility and reduce the cholesterol biosynthesis.

Date of Submisson/Request
2021-01-29
Date of Acceptance
2021-04-13
Date of Publication
2021-04-31

Where published
Journal of Functional Foods

Publication Identifiers
ISSN - 1756-4646

Volume
83

Starting page
104567

Document Identifiers
DOI - https://doi.org/10.1016/j.jff.2021.104567
URL - http://dx.doi.org/10.1016/j.jff.2021.104567

Rankings
CITESCORE (until 2019) (2019) -
SCIMAGO Q1 (2020) - 0.994 - Food Science
Web Of Science Q1 (2020) - 4.451 - FOOD SCIENCE & TECHNOLOGY - SCIE


Export

APA
Pedro B., Guedes L., André R, Gaspar M.H., Vaz P., Ascensão L., Melo R., Serralheiro M.L., (2021). Undaria pinnatifida (U. pinnatifida) bioactivity: antioxidant, gastro-intestinal motility, cholesterol biosynthesis and liver cell lines proteome. Journal of Functional Foods, 83, ISSN 1756-4646. eISSN . http://dx.doi.org/10.1016/j.jff.2021.104567

IEEE
Pedro B., Guedes L., André R, Gaspar M.H., Vaz P., Ascensão L., Melo R., Serralheiro M.L., "Undaria pinnatifida (U. pinnatifida) bioactivity: antioxidant, gastro-intestinal motility, cholesterol biosynthesis and liver cell lines proteome" in Journal of Functional Foods, vol. 83, 2021. https://doi.org/10.1016/j.jff.2021.104567

BIBTEX
@article{52011, author = {Pedro B. and Guedes L. and André R and Gaspar M.H. and Vaz P. and Ascensão L. and Melo R. and Serralheiro M.L.}, title = {Undaria pinnatifida (U. pinnatifida) bioactivity: antioxidant, gastro-intestinal motility, cholesterol biosynthesis and liver cell lines proteome}, journal = {Journal of Functional Foods}, year = 2021, volume = 83 }