BIBLIOS

  Sistema de Gestão de Referências Bibliográficas de Ciências

Modo Visitante (Login)
Need help?


Voltar

Detalhes Referência

Tipo
Artigos em Revista

Tipo de Documento
Artigo Completo

Título
Assessment of out-of-field doses in radiotherapy treatments of paediatric patients using Monte Carlo methods and measurements

Participantes na publicação
Ana Cravo Sá (Author)
Andreia Barateiro (Author)
Bryan Bednarz (Author)
Cecília Borges (Author)
Joana Pereira (Author)
Mariana Baptista (Author)
Miguel Pereira (Author)
Miriam Zarza-Moreno (Author)
Pedro Almeida (Author)
Dep. Física
IBEB
Pedro Vaz (Author)
Tiago Madaleno (Author)
Yuriy Romanets (Author)

Resumo
Purpose: To assess out-of-field doses in radiotherapy treatments of paediatric patients, using Monte Carlo methods to implement a new model of the linear accelerator validated against measurements and developing a voxelized anthropomorphic paediatric phantom.Methods: CT images of a physical anthropomorphic paediatric phantom were acquired and a dosimetric planning using a TPS was obtained. The CT images were used to perform the voxelization of the physical phantom using the ImageJ software and later implemented in MCNP. In order to validate the Monte Carlo model, dose measurements of the 6 MV beam and Linac with 120 MLC were made in a clinical setting, using ionization chambers and a water phantom. Afterwards TLD measurements in the physical anthropomorphic phantom were performed in order to assess the out-of-field doses in the eyes, thyroid, c-spine, heart and lungs. Results: The Monte Carlo model was validated for in-field and out-of-field doses with average relative differences below 3%. The average relative differences between TLD measurements and Monte Carlo is 14,3% whilst the average relative differences between TLD and TPS is 55,8%. Moreover, organs up to 22.5 cm from PTV center show TLD and MCNP6 relative differences and TLD and TPS relative differences up to 21.2% and 92.0%, respectively. Conclusions: Our study provides a novel model that could be used in clinical research, namely in dose evaluation outside the treatment fields. This is particularly relevant, especially in pediatric patients, for studying new radiotherapy treatment techniques, since it can be used to estimate the development of secondary tumours.

Data de Publicação
2020-03

Suporte
Physica Medica

Identificadores da Publicação
ISSN - 1120-1797

Editora
Elsevier BV

Volume
71

Número de Páginas
8
Página Inicial
53
Página Final
61

Identificadores do Documento
DOI - https://doi.org/10.1016/j.ejmp.2020.02.008
URL - http://dx.doi.org/10.1016/j.ejmp.2020.02.008

Identificadores de Qualidade
SCOPUS Q1 (2019) - 4.1 - Radiology, Nuclear Medicine and Imaging

Keywords
Out-of-field doses Clinical measurements Monte Carlo methods Anthropomorphic paediatric phantom


Exportar referência

APA
Ana Cravo Sá, Andreia Barateiro, Bryan Bednarz, Cecília Borges, Joana Pereira, Mariana Baptista, Miguel Pereira, Miriam Zarza-Moreno, Pedro Almeida, Pedro Vaz, Tiago Madaleno, Yuriy Romanets, (2020). Assessment of out-of-field doses in radiotherapy treatments of paediatric patients using Monte Carlo methods and measurements. Physica Medica, 71, 53-61. ISSN 1120-1797. eISSN . http://dx.doi.org/10.1016/j.ejmp.2020.02.008

IEEE
Ana Cravo Sá, Andreia Barateiro, Bryan Bednarz, Cecília Borges, Joana Pereira, Mariana Baptista, Miguel Pereira, Miriam Zarza-Moreno, Pedro Almeida, Pedro Vaz, Tiago Madaleno, Yuriy Romanets, "Assessment of out-of-field doses in radiotherapy treatments of paediatric patients using Monte Carlo methods and measurements" in Physica Medica, vol. 71, pp. 53-61, 2020. 10.1016/j.ejmp.2020.02.008

BIBTEX
@article{43638, author = {Ana Cravo Sá and Andreia Barateiro and Bryan Bednarz and Cecília Borges and Joana Pereira and Mariana Baptista and Miguel Pereira and Miriam Zarza-Moreno and Pedro Almeida and Pedro Vaz and Tiago Madaleno and Yuriy Romanets}, title = {Assessment of out-of-field doses in radiotherapy treatments of paediatric patients using Monte Carlo methods and measurements}, journal = {Physica Medica}, year = 2020, pages = {53-61}, volume = 71 }