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Publication details

Document type
Journal articles

Document subtype
Full paper

Title
Assessment of out-of-field doses in radiotherapy treatments of paediatric patients using Monte Carlo methods and measurements

Participants in the publication
Ana Cravo Sá (Author)
Andreia Barateiro (Author)
Bryan Bednarz (Author)
Cecília Borges (Author)
Joana Pereira (Author)
Mariana Baptista (Author)
Miguel Pereira (Author)
Miriam Zarza-Moreno (Author)
Pedro Almeida (Author)
Dep. Física
 IBEB
 Pedro Vaz (Author)
Tiago Madaleno (Author)
Yuriy Romanets (Author)

Summary
Purpose: To assess out-of-field doses in radiotherapy treatments of paediatric patients, using Monte Carlo methods to implement a new model of the linear accelerator validated against measurements and developing a voxelized anthropomorphic paediatric phantom.Methods: CT images of a physical anthropomorphic paediatric phantom were acquired and a dosimetric planning using a TPS was obtained. The CT images were used to perform the voxelization of the physical phantom using the ImageJ software and later implemented in MCNP. In order to validate the Monte Carlo model, dose measurements of the 6 MV beam and Linac with 120 MLC were made in a clinical setting, using ionization chambers and a water phantom. Afterwards TLD measurements in the physical anthropomorphic phantom were performed in order to assess the out-of-field doses in the eyes, thyroid, c-spine, heart and lungs. Results: The Monte Carlo model was validated for in-field and out-of-field doses with average relative differences below 3%. The average relative differences between TLD measurements and Monte Carlo is 14,3% whilst the average relative differences between TLD and TPS is 55,8%. Moreover, organs up to 22.5 cm from PTV center show TLD and MCNP6 relative differences and TLD and TPS relative differences up to 21.2% and 92.0%, respectively. Conclusions: Our study provides a novel model that could be used in clinical research, namely in dose evaluation outside the treatment fields. This is particularly relevant, especially in pediatric patients, for studying new radiotherapy treatment techniques, since it can be used to estimate the development of secondary tumours.

Date of Publication
2020-03

Where published
Physica Medica

Publication Identifiers
ISSN - 1120-1797

Publisher
Elsevier BV

Volume
71

Number of pages
8
Starting page
53
Last page
61

Document Identifiers
DOI - https://doi.org/10.1016/j.ejmp.2020.02.008
URL - http://dx.doi.org/10.1016/j.ejmp.2020.02.008

Rankings
SCOPUS Q1 (2019) - 4.1 - Radiology, Nuclear Medicine and Imaging

Keywords
Out-of-field doses Clinical measurements Monte Carlo methods Anthropomorphic paediatric phantom


Export

APA
Ana Cravo Sá, Andreia Barateiro, Bryan Bednarz, Cecília Borges, Joana Pereira, Mariana Baptista, Miguel Pereira, Miriam Zarza-Moreno, Pedro Almeida, Pedro Vaz, Tiago Madaleno, Yuriy Romanets, (2020). Assessment of out-of-field doses in radiotherapy treatments of paediatric patients using Monte Carlo methods and measurements. Physica Medica, 71, 53-61. ISSN 1120-1797. eISSN . http://dx.doi.org/10.1016/j.ejmp.2020.02.008

IEEE
Ana Cravo Sá, Andreia Barateiro, Bryan Bednarz, Cecília Borges, Joana Pereira, Mariana Baptista, Miguel Pereira, Miriam Zarza-Moreno, Pedro Almeida, Pedro Vaz, Tiago Madaleno, Yuriy Romanets, "Assessment of out-of-field doses in radiotherapy treatments of paediatric patients using Monte Carlo methods and measurements" in Physica Medica, vol. 71, pp. 53-61, 2020. 10.1016/j.ejmp.2020.02.008

BIBTEX
@article{43638, author = {Ana Cravo Sá and Andreia Barateiro and Bryan Bednarz and Cecília Borges and Joana Pereira and Mariana Baptista and Miguel Pereira and Miriam Zarza-Moreno and Pedro Almeida and Pedro Vaz and Tiago Madaleno and Yuriy Romanets}, title = {Assessment of out-of-field doses in radiotherapy treatments of paediatric patients using Monte Carlo methods and measurements}, journal = {Physica Medica}, year = 2020, pages = {53-61}, volume = 71 }