Document type
Journal articles
Document subtype
Full paper
Title
Proof of Concept of an Integrated Laser Irradiation and Thermal/Visible Imaging System for Optimized Photothermal Therapy in Skin Cancer
Participants in the publication
Diogo Novas (Author)
Alessandro Fortes (Author)
Pedro Vieira (Author)
João M. P. Coelho (Author)
Dep. Física
IBEB
Summary
Laser energy is widely used as a selective photothermal heating agent in cancer treatment, standing out for not relying on ionizing radiation. However, in vivo tests have highlighted the need to develop irradiation techniques that allow precise control over the illuminated area, adapting it to the tumor size to further minimize damage to surrounding healthy tissue. To address this challenge, a proof of concept based on a laser irradiation system has been designed, enabling control over energy, exposure time, and irradiated area, using galvanometric mirrors. The control software, implemented in Python, employs a set of cameras (visible and infrared) to detect and monitor real-time thermal distributions in the region of interest, transmitting this information to a microcontroller responsible for adjusting the laser power and controlling the scanning process. Image alignment procedures, tunning of the controller’s gain parameters and the impact of the different engineering parameters are illustrated on a dedicated setup.
Date of Publication
2025-07-19
Where published
Sensors
Publication Identifiers
ISSN - 1424-8220
Publisher
MDPI AG
Document Identifiers
DOI -
https://doi.org/10.3390/s25144495
URL -
https://doi.org/10.3390/s25144495
Rankings
SCOPUS Q1 (2023) - 7.3 - Instrumentation