BIBLIOS

Tipo
Artigos em Revista

Tipo de Documento
Artigo Completo

Título
Targeting superficial cancers with gold nanoparticles: a review of current research

Participantes na publicação
Susana M Gomes (Author)
Maria Manuela Gaspar (Author)
João MP Coelho (Author)
Dep. Física
IBEB
Catarina Pinto Reis (Author)

Resumo
Superficial cancers typically refer to cancers confined to the surface layers of tissue. Low-targeting therapies or side effects prompt exploration of novel therapeutic approaches. Gold nanoparticles (AuNPs), due to their unique optical properties, serve as effective photosensitizers, enabling tumor ablation through photothermal therapy (PTT). PTT induced by AuNPs can be achieved through light sources externally applied to the skin. Near-infrared radiation is the main light candidate due to its deep tissue penetration capability. This review explores recent advancements in AuNP-based PTT for superficial cancers, specifically breast, head and neck, thyroid, bladder and prostate cancers. Additionally, challenges and future directions in utilizing AuNPs for cancer treatment are discussed, emphasizing the importance of balancing efficacy with safety in clinical applications.


Suporte
Therapeutic Delivery

Identificadores da Publicação
ISSN - 2041-5990

Editora
Informa UK Limited


Identificadores do Documento
DOI - https://doi.org/10.1080/20415990.2024.2395249
URL - http://dx.doi.org/10.1080/20415990.2024.2395249

Identificadores de Qualidade
SCIMAGO Q2 (2023) - 0.46 - Pharmaceutical Science