Document type
Journal articles
Document subtype
Full paper
Title
Targeting superficial cancers with gold nanoparticles: a review of current research
Participants in the publication
Susana M Gomes (Author)
Maria Manuela Gaspar (Author)
João MP Coelho (Author)
Dep. Física
IBEB
Catarina Pinto Reis (Author)
Summary
Superficial cancers typically refer to cancers confined to the surface layers of tissue. Low-targeting therapies or side effects prompt exploration of novel therapeutic approaches. Gold nanoparticles (AuNPs), due to their unique optical properties, serve as effective photosensitizers, enabling tumor ablation through photothermal therapy (PTT). PTT induced by AuNPs can be achieved through light sources externally applied to the skin. Near-infrared radiation is the main light candidate due to its deep tissue penetration capability. This review explores recent advancements in AuNP-based PTT for superficial cancers, specifically breast, head and neck, thyroid, bladder and prostate cancers. Additionally, challenges and future directions in utilizing AuNPs for cancer treatment are discussed, emphasizing the importance of balancing efficacy with safety in clinical applications.
Date of Publication
2024-09-24
Where published
Therapeutic Delivery
Publication Identifiers
ISSN - 2041-5990
Publisher
Informa UK Limited
Number of pages
19
Starting page
1
Last page
19
Document Identifiers
DOI -
https://doi.org/10.1080/20415990.2024.2395249
URL -
http://dx.doi.org/10.1080/20415990.2024.2395249
Rankings
SCIMAGO Q2 (2023) - 0.46 - Pharmaceutical Science