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Detalhes Referência

Tipo
Artigos em Conferência

Tipo de Documento
Artigo Completo

Título
Oleic acid enhances the production of reactive oxygen species in neuronal tissue

Participantes na publicação
J.L. Alves (Author)
UNIVERSIDADE DE COIMBRA
 A.S.C. Figueira (Author)
UNIVERSIDADE DE COIMBRA
 M. Souto (Author)
UNIVERSIDADE DE COIMBRA
 I.L. Lopes (Author)
UNIVERSIDADE DE COIMBRA
 J.C. Dionísio (Author)
Dep. Biologia Animal
 R.M. Quinta-Ferreira (Author)
UNIVERSIDADE DE COIMBRA
 M.E. Quinta-Ferreira (Author)
CENTRO DE NEUROCIÊNCIAS E BIOLOGIA CELULAR
Resumo
One of the major current goals is to obtain clean energy sources and to replace petroleum-derived fuel by biodiesel, which is made from biodegradable and renewable biomass such as vegetable oils. In particular, olive oil contains large amounts of oleic acid (OA), which is a monounsaturated fatty acid used for energy production and also for biosensors, nutritional products, pharmaceuticals and cosmetics. Since oleic acid is particularly abundant in olive oil, large concentrations of this fatty acid may exist in the effluents of olive mill production units, which need to be treated in order to avoid water contaminations and undesirable effects in the ecosystem. Indeed, this type of organic waste, which is potentially useful in the production of biodiesel, in excess may be toxic and cause neurodegeneration, through the production of cellular reactive oxygen species (ROS). The effect of 10–100 M of oleic acid on neuronal ROS production was evaluated in brain slices incubated with the permeant fluorescent ROS indicator DCFDA. The experiments revealed that the amplitude of the ROS signals, corrected for the autofluorescence, increased slightly for the OA concentrations in the range 60–100 M.

Data de Submissão/Pedido
2019-11-19
Data de Aceitação
2019-11-22
Data de Publicação
2020-03-02

Evento
Energy Reports

Identificadores da Publicação
ISSN - 23524847

Editora
Elsevier BV

Volume
6

Número de Páginas
6
Página Inicial
885
Página Final
890

Identificadores do Documento
DOI - https://doi.org/10.1016/j.egyr.2019.11.034
URL - http://dx.doi.org/10.1016/j.egyr.2019.11.034

Identificadores de Qualidade
SCIMAGO Q1 (2020) - 1.199 - Energy (miscellaneous)


Exportar referência

APA
J.L. Alves, A.S.C. Figueira, M. Souto, I.L. Lopes, J.C. Dionísio, R.M. Quinta-Ferreira, M.E. Quinta-Ferreira, (2020). Oleic acid enhances the production of reactive oxygen species in neuronal tissue. Energy Reports, 885-890

IEEE
J.L. Alves, A.S.C. Figueira, M. Souto, I.L. Lopes, J.C. Dionísio, R.M. Quinta-Ferreira, M.E. Quinta-Ferreira, "Oleic acid enhances the production of reactive oxygen species in neuronal tissue" in Energy Reports, , 2020, pp. 885-890, doi: 10.1016/j.egyr.2019.11.034

BIBTEX
@InProceedings{55036, author = {J.L. Alves and A.S.C. Figueira and M. Souto and I.L. Lopes and J.C. Dionísio and R.M. Quinta-Ferreira and M.E. Quinta-Ferreira}, title = {Oleic acid enhances the production of reactive oxygen species in neuronal tissue}, booktitle = {Energy Reports}, year = 2020, pages = {885-890}, address = {}, publisher = {Elsevier BV} }