BIBLIOS

Tipo
Artigos em Revista

Tipo de Documento
Artigo Completo

Título
Evolution in the light of fitness landscape theory

Participantes na publicação
Inês Fragata (Author)
INSTITUTO GULBENKIAN DE CIÊNCIA
Dep. Biologia Animal
cE3c
Alexandre Blanckaert (Author)
INSTITUTO GULBENKIAN DE CIÊNCIA
Marco António Dias Louro (Author)
INSTITUTO GULBENKIAN DE CIÊNCIA
David A. Liberles (Author)
Claudia Bank (Author)
INSTITUTO GULBENKIAN DE CIÊNCIA

Resumo
By formalizing the relationship between genotype or phenotype and fitness, fitness landscapes harbor information on molecular and evolutionary constraints. The shape of the fitness landscape determines the potential for adaptation and speciation, as well as our ability to predict evolution. Consequently, fitness landscape theory has been invoked across the natural sciences and across multiple levels of biological organization. We review here the existing literature on fitness landscape theory by describing the main types of fitness landscape models, and highlight how these are increasingly integrated into an applicable statistical framework for the study of evolution. Specifically, we demonstrate how the interpretation of experimental studies with respect to fitness landscape models enables a direct link between evolution, molecular biology, and systems biology.


Instituição
INSTITUTO GULBENKIAN DE CIÊNCIA

Suporte
Trends in Ecology & Evolution

Identificadores da Publicação
ISSN - 0169-5347

Editora
Elsevier BV



Identificadores do Documento
DOI - https://doi.org/10.1016/j.tree.2018.10.009
URL - http://dx.doi.org/10.1016/j.tree.2018.10.009

Identificadores de Qualidade
SCOPUS Q1 (2011) - 11.146 - Ecology, Evolution, Behavior and Systematics
Web Of Science Q1 (2017) - 15.938 - GENETICS & HEREDITY - SCIE

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