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Publication details

Document type
Journal articles

Document subtype
Full paper

Title
Structural reorganization renders enhanced metalloprotein stability

Participants in the publication
Hugo M. Botelho (Author)
Cláudio M. Gomes (Author)
Dep. Química e Bioquímica
BioISI

Summary
The enhanced stability of a mesophilic metalloprotein was assessed using biophysical spectroscopies. Significant local structural interconversions during thermal insult account for a reorganization of the protein scaffold, without disturbing the active metal site. This cushioning mechanism is proposed to be a generic property of metalloproteins contributing to enhanced stability.

Date of Submisson/Request
2011-06-06
Date of Acceptance
2011-08-24
Date of Publication
2011-09-06

Institution
INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA

Where published
Chemical Communications

Publication Identifiers
ISSN - 1359-7345
eISSN - 1364-548X

Publisher
Royal Society of Chemistry (RSC)

Volume
47
Number
39

Starting page
11149

Document Identifiers
DOI - https://doi.org/10.1039/c1cc13354c
URL - http://dx.doi.org/10.1039/c1cc13354c


Export

APA
Hugo M. Botelho, Cláudio M. Gomes, (2011). Structural reorganization renders enhanced metalloprotein stability. Chemical Communications, 47, ISSN 1359-7345. eISSN 1364-548X. http://dx.doi.org/10.1039/c1cc13354c

IEEE
Hugo M. Botelho, Cláudio M. Gomes, "Structural reorganization renders enhanced metalloprotein stability" in Chemical Communications, vol. 47, 2011. 10.1039/c1cc13354c

BIBTEX
@article{39290, author = {Hugo M. Botelho and Cláudio M. Gomes}, title = {Structural reorganization renders enhanced metalloprotein stability}, journal = {Chemical Communications}, year = 2011, volume = 47 }